Enzyme Inhibitors for Glycolipids

Matreya offers inhibitors that will stop the enzymatic metabolism of glycolipids at various points in their biosynthetic routes. PDMP and PPMP are well known inhibitors of glucosylceramide synthase and both active and inactive isomers are available for comparison studies. Safingol is an important inhibitor of protein kinase C which controls the function of proteins through phosphorylation. Acid and alkaline ceramidase inhibitors, including NOE and D-MAPP, prevent the metabolism of ceramide to sphingosine.
19 Product(s)
  1. 2-Acetyl-4-(1R,2S,3R,-4-tetrahydroxybutyl)-imidazole (1858)

    £140.63
    Product Size: 1 mg
    2-Acetyl-4-tetrahydroxybutylimidazole (THI)
  2. 2-Fluoropalmitic acid (1717)

    £206.25
    Product Size: 25 mg
    2-Fluoropalmitic acid Activity: Acyl-CoA synthase inhibitor
  3. Conduritol B Epoxide (1889)

    £253.13
    Product Size: 25 mg
    D,L-1,2-Anhydro-myo-inositol; Inhibits alpha-glucosidase activity; specific inhibitor of glucocerebrosidase in cultured cells
  4. D,L-erythro-PDMP (1755)

    £220.31
    Product Size: 100 mg
    D,L-erythro-1-Phenyl-2-decanoylamino-3-morpholino-1-propanol•HCl
  5. D,L-erythro-PPMP (1753)

    £220.31
    Product Size: 100 mg
    D,L-erythro-1-Phenyl-2-hexadecanoylamino-3-morpholino-1-propanol•HCl
  6. D,L-threo-PDMP (1719)

    £234.38
    Product Size: 100 mg
    D,L-threo-1-Phenyl-2-decanoylamino-3-morpholino-1-propanol•HCl Activity: glucosylceramide synthase inhibitor
  7. D,L-threo-PPMP (1720)

    £234.38
    Product Size: 100 mg
    D,L-threo-l-Phenyl-2-hexadecanoylamino-3-morpholino-propanol·HCl Activity: glucosylceramide synthase inhibitor
  8. D-erythro-2-Tetradecanoylamino-1-phenyl-1-propanol, (D-MAPP) (1859)

    £196.88
    Product Size: 100 mg
    D-erythro-2-Tetradecanoylamino-1-phenyl-1-propanol Activity: alkaline ceramidase inhibitor
  9. D-threo-PDMP (1756)

    £323.44
    Product Size: 10 mg
    D-threo-1-Phenyl-2-decanoylamino-3-morpholino-1-propanol•HCl; Activity: glucosylceramide synthase inhibitor
  10. D-threo-PPMP (1865)

    £304.69
    Product Size: 10 mg
    D-threo-1-Phenyl-2-hexadecanoylamino-3-morpholino-1-propanol•HCl Activity: glucosylceramide synthase inhibitor
  11. L-erythro-2-Tetradecanoylamino-1-phenyl-1-propanol, (L-MAPP) (1860)

    £196.88
    Product Size: 100 mg
    L-erythro-2-Tetradecanoylamino-1-phenyl-1-propanol Activity: inactive as alkaline ceramidase inhibitor
  12. L-threo-Dihydrosphingosine (Safingol) (1807)

    Starting at: £225.00

    L-threo-Sphinganine, C18 chain
  13. L-threo-PDMP (1749)

    £365.63
    Product Size: 10 mg
    L-threo-1-Phenyl-2-decanoylamino-3-morpholino-1-propanol•HCl
  14. L-threo-PPMP (1868)

    £304.69
    Product Size: 10 mg
    L-threo-1-Phenyl-2-hexadecanoylamino-3-morpholino-1-propanol•HCl
  15. Methyl 2-fluoropalmitate (1718)

    £206.25
    Product Size: 10 mg
    Methyl 2-fluoropalmitate Activity: inactive ester of 2-fluoropalmitic acid
  16. N-(1-Adamantaneacetyl)-ceramide trihexoside (1947)

    £393.75
    Product Size: 1 mg
    N-Adamantyl-globotriaosylceramide; AdaGb3
  17. N-(1-Adamantaneacetyl)-galactosylceramide (1946)

    £393.75
    Product Size: 5 mg
    N-(1-Adamantaneacetyl)-galactocerebroside
  18. N-(1-Adamantaneacetyl)-glucosylceramide (1945)

    £393.75
    Product Size: 5 mg
    N-(1-Adamantaneacetyl)-glucocerebroside
  19. N-Oleoylethanolamine (1751)

    £215.63
    Product Size: 100 mg
    NOE; Activity: acid ceramidase inhibitor