Recombinant Mouse APRIL

A proliferation-inducing ligand (APRIL) is a TNF-like cytokine that stimulates tumor cell growth.¹ It is of low abundance in normal tissues.² APRIL acts as a proliferative factor in megakaryocytopoiesis, a developmental hematopoietic process responsible for progenitor cell differentiation to megakaryoblasts and megakaryocytes, leading to platelet formation.³ APRIL may be implicated in the regulation of tumor cell growth.²