Recombinant Human TrkB

Tropomyosin-related kinase B (TrkB) is a receptor for neurotrophins, a family of closely related proteins that are important physiological regulators of the survival of specific neurons within the peripheral nervous system (PNS) of vertebrates.¹ TrkB is an independent prognostic marker in patients with gastric cancer and appears to be associated with metastatic potential.² Trk-B pathway down-regulation may be the major pathogenesis for Major depressive disorder (MDD).²