Recombinant Human PDGF-AB
Recombinant Human PDGF-AB (P128-GRP)
Products
Description
Platelet-derived growth factor AB (PDGF-AB) is a heterodimeric1 non-glycosylated polypeptide isomer of PDGF.2 The biological effects of PDGF are mediated by cell surface alpha and beta PDGF receptors, which, as a result of ligand binding, undergo dimerization.3 PDGF-AB interaction with the alpha PDGF receptor induces conformational changes in the ligand or receptor that facilitates efficient recruitment of beta PDGFR by this PDGF isoform.4 However, PDGF-AA is not likely to be physiologically significant activators of cells unless the cells express PDGFR alpha.5 PDGF-AB may promote wound healing by stimulating extracellular matrix synthesis, e.g. collagen. It may also play a role in scar formation through collagen deposition.6
Specifications
| Manufacturer | Leinco Technologies Inc |
|---|---|
| Manufacturer Cat# | P128 |
| Formulation | This recombinant protein was lyophilized from a 0.2 μm filtered solution in 30% acetonitrile (CH3CN) and 0.1% trifluoroacetic acid (TFA). |
| Alternate Names | Platelet Derived Growth Factor-AB Platelet Derived Growth FactorAB Platelet Derived Growth Factor AB Recombinant Human PDGF-AB PDGF-AB PDGFAB PDGF AB Recombinant Human PDGF-AB Glioma-Derived Growth Factor GDGF Osteosarcoma-Derived Growth Factor ODGF GliomaDerived Growth Factor GDGF OsteosarcomaDerived Growth Factor ODGF Glioma Derived Growth Factor GDGF Osteosarcoma Derived Growth Factor ODGF Recombinant Human PDGF-AB Recombinant Protein Platelet Derived Growth Factor-AB Glioma-Derived Growth Factor GDGF Osteosarcoma-Derived Growth Factor ODGF PDGF-AB Human Recombinant Human PDGF-AB Recombinant Protein Platelet Derived Growth FactorAB GliomaDerived Growth Factor GDGF OsteosarcomaDerived Growth Factor ODGF PDGFAB Human Recombinant Human PDGFAB Recombinant Protein Platelet Derived Growth Factor AB Glioma Derived Growth Factor GDGF Osteosarcoma Derived Growth Factor ODGF PDGF AB Human Recombinant Human PDGF AB Recombinant Human PDGF-AB |
| Target | PDGF-AB |
| Storage | -20°C to -70°C |
| Protein | PDGF-AB |