Methyl 3-hydroxytetradecanoateMethyl 3-hydroxytetradecanoate
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Methyl 3-hydroxytetradecanoate

3-Hydroxy C14:0 methyl ester

This methyl 3-hydroxytetradecanoate is a high purity standard that is useful for the investigation of disorders and diseases. Polyhydroxyalkenoates, polyesters produced by bacteria fermentation, are used for carbon and energy storage and are of interest in studies regarding their synthesis, properties and mechanisms. Medium chain-length polyhydroxyalkenoate monomers such as 3-hydroxytetradecanoic acid may have pharmaceutical properties. The biologically natural chiral (R)-3- hydroxytetradecanoic acid is an intermediate in fatty acid biosynthesis. 3-hydroxytetradecanoic acid has been shown to have critical functions in bacteria.1 It has also been proposed as a measure for endotoxins from cotton lint and dust at high levels.2 3-hydroxy fatty acids are used as biomarkers for fatty acid oxidative disorders of both the long- and short-chain 3-hydroxyacyl- CoA dehydrogenases.3,4
Cat# Size Price Qty Buy
1736 25 mg £178.13

Additional Information

Property Value or Rating
Product Size 25 mg
Manufacturer Matreya, LLC
Empirical Formula C15H30O3
CAS# 55682-83-2
Formula Weight 258.4
Solvent none
Source synthetic
Purity 98+%
Analytical Methods TLC, GC, identity confirmed by MS
Natural Source Synthetic
Melting Point 36-37°C
Solubility chloroform, methanol, ethyl ether
Physical Appearance A neat solid
Storage -20°C
References

1. E. Rietschel et al. “Structural studies on the lipid A component of enterobacterial lipopolysaccharides by laser desorption mass spectrometry. Location of acyl groups at the lipid A backbone” Eur J Biochem, vol. 145 pp. 505-509, 1984 
2. R. Berni et al. “3-Hydroxymyristic acid as a measure of endotoxin in cotton lint and dust” Am Ind Hyg Assoc J, vol. 49 pp. 81-88, 1988 
3. P. Jones et al. “Improved Stable Isotope Dilution-Gas Chromatography-Mass Spectrometry Method for Serum or Plasma Free 3-Hydroxy-Fatty Acids and Its Utility for the Study of Disorders of Mitochondrial Fatty Acid beta-Oxidation” Clinical Chemistry, vol. 46, pp. 149-155, 2000 
4. P. Jones et al. “Accumulation of free 3-hydroxy fatty acids in the culture media of fibroblasts from patients deficient in long-chain l-3-hydroxyacyl-CoA dehydrogenase: a useful diagnostic aid” Clinical Chemistry, vol. 47(7) pp. 1190-1194, 2001

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