Human NOV ELISA Development Kit

Nephroblastoma overexpressed gene, also known as NOV is a member of the CCN (connective tissue growth factor [CTGF]) family of proteins. These proteins are cysteine-rich and are noted for having growth-regulatory functions.1 NOV is highly expressed in the nervous system.2 NOV is a specific cell fate regulator in the myogenic lineage, acting negatively on key myogenic genes thus controlling the transition from progenitor cells to myoblasts.3 NOV also supports endothelial cell adhesion and angiogenesis through interactions with integrins.4