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(R)-(-)-Gossypol acetic acid(R)-(-)-Gossypol acetic acid
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(R)-(-)-Gossypol acetic acid

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(R)-(-)-Gossypol (AT-101) acetic acid, the R-(-) enantiomer of Gossypol acetic acid, binds with Bcl-2, Bcl-xL and Mcl-1 with Ki of 0.32 μM, 0.48 μM and 0.18 μM in cell-free assays; does not inhibit BIR3 domain and BID. AT-101 simultaneously triggers apoptosis and a cytoprotective type of autophagy. Phase 2.
Cat# Size Price Qty Buy
S2812-50mg 50mg
£384.00
S2812-10mM/1mL 10mM/1mL
£155.00
S2812-10mg 10mg
£120.00

Additional Information

Property Value or Rating
Manufacturer Selleck Chemicals LLC
Manufacturer Cat# S2812

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