anti- TNFR1 antibody

anti- TNFR1 antibody

Receptor for TNFSF2/TNF-alpha and homotrimeric TNFSF1/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex(DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases(aspartate-specific cysteine proteases) mediating apoptosis. Contributes to the induction of non-cytocidal TNF effects including anti-viral state and activation of the acid sphingomyelinase.
Cat# Size Price Qty Buy
FNab08823 100µg £245.00

Additional Information

Property Value or Rating
Product Size 100µg
Manufacturer FineTest
Antibody Type monoclonal
Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Physical Appearance liquid
Purification Protein A+G purification
Purity ≥95% as determined by SDS-PAGE
Host Mouse
Isotype IgG1
Immunogen tumor necrosis factor receptor superfamily, member 1A
Alternate Names CD120a, FPF, p55, p55 R, p60, TBP1, TBPI, TNF R, TNF R I, TNF R1, TNF R55, TNF Receptor 1, TNF Receptor I, TNF RI, TNFAR, TNFR I, TNFR1, TNFR55, TNFR60, TNFRSF1A
Calculated MW 50 kDa
Protein ID P19438
Clone 1G4
Reactivity Human, Mouse
Applications ELISA, FC, IHC, WB
Recommended dilution WB: 1:500-1:5000; IHC: 1:50-1:500

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