Anti-Mouse Ly-6G - Purified In vivo PLATINUM™ Functional GradeAnti-Mouse Ly-6G - Purified In vivo PLATINUM™ Functional Grade
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Anti-Mouse Ly-6G - Purified In vivo PLATINUM™ Functional Grade

Ly6G antibody, clone 1A8, recognizes lymphocyte antigen 6 complex locus G6D (Ly6G; also called Gr-1), a 21-25 kDa glycosylphosphatidylinositol (GPI)-anchored protein1. Ly6G belongs to the lymphocyte antigen-6 (Ly6)/urokinase-type plasminogen activator receptor (uPAR) superfamily, characterized by a Ly6/uPAR (LU) domain-containing a three-fingered structural motif stabilized by disulfide bonds2. Ly6G is expressed by murine neutrophils regardless of location and activation1,4,5. Eosinophils may also express low levels of Ly6G5. There is no human ortholog for Ly6G; however, a structurally related L76/uPAR protein, CD177 (also known as HNA-2a, NB1, or PRV-1) is expressed in human neutrophils and is implicated in neutropenia6. Although the exact function and ligand of Ly6G remain unknown, Ly6G ligation may impair neutrophil migration to sites of inflammation via a β2-integrin-dependent mechanism7.
Cat# Size Price Qty Buy
L305-100mg 100 mg
£2,625.00
L305-50mg 50 mg
£1,917.19
L305-25mg 25 mg
£1,204.69
L305-5.0mg 5.0 mg
£417.19
L305-1.0mg 1.0 mg
£210.94

Additional Information

Property Value or Rating
Manufacturer Cat# L305
Concentration ≥ 5.0 mg/ml
Formulation This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.2 - 7.4 with no carrier protein, potassium, calcium or preservatives added.
Manufacturer Leinco Technologies Inc
Isotype IgG2a
Clone 1A8
Antibody Type Monoclonal
Applications CODEX®, CyTOF®, Depletion, FC, IHC FF, WB
Antigen Ly6G is expressed by neutrophils.
Storage Functional grade preclinical antibodies may be stored sterile as received at 2-8°C for up to one month. For longer term storage, aseptically aliquot in working volumes without diluting and store at -80°C. Avoid Repeated Freeze Thaw Cycles.
Protein Ly-6G

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