Anti-Mouse CD54 (Clone YN1/1.7.4) - Purified In vivo PLATINUM™ Functional Grade

ICAM-1 is a 55 kDa glycoprotein that is part of the Ig superfamily. It is heavily glycosylated to form 75 kDa to 115 kDa. ICAM-1 is known to be an adhesion and viral entry molecule, and its long suspected involevement in signal transduction is being elucidated. The signal-transducing functions of ICAM-1 appear to be mainly associated with proinflammatory pathways. Furthermore, ICAM-1 signaling appears to act as a beacon for inflammatory immune cells such as macrophages and granulocytes bringing about inflammation via lymphocyte trafficking. ICAM-1 is essential for the transmigration of leukocytes out of blood vessels and into tissues, and is a marker of endothelial dysfunction leading to damaging vascular disorders in umbilical and placental vascular tissue of gestational pregnancies. ICAM-1 is the receptor for rhinoviruses (the cause of most common colds) and malaria, and plays an inflammatory role in ocular allergies.
Cat# Size Price Qty Buy
C6391-100mg 100 mg
£2,625.00
C6391-50mg 50 mg
£1,917.19
C6391-25mg 25 mg
£1,204.69
C6391-5.0mg 5.0 mg
£417.19
C6391-1.0mg 1.0 mg
£210.94

Additional Information

Property Value or Rating
Manufacturer Cat# C6391
Concentration ≥ 5.0 mg/ml
Formulation This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.2 - 7.4 with no carrier protein, potassium, calcium or preservatives added.
Manufacturer Leinco Technologies Inc
Isotype IgG2b κ
Clone YN1/1.7.4
Applications CODEX®, CyTOF®, FA, FC, IHC FF, IP, WB
Antigen CD54 is present on endothelial cells, lymphocytes, epithelial cells, dendritic cells and keratinocytes.
Storage Functional grade preclinical antibodies may be stored sterile as received at 2-8°C for up to one month. For longer term storage, aseptically aliquot in working volumes without diluting and store at -80°C. Avoid Repeated Freeze Thaw Cycles.
Protein CD54

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