Anti-globoside GL4, (rabbit)Anti-globoside GL4, (rabbit)
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Anti-globoside GL4, (rabbit)

Polyclonal antibody to GL-4, isotype IgG/IgM

Anti-globosides are very useful in the identification of globosides and immunotargeting cells that express globosides. Globoside is the P-antigen of the P blood group. An inability to convert globotriaosylceramide to globotetrahexylceramide leads to the Pk blood group phenotype. In this phenotype anti-globoside antibodies are produced.3 There have been indications that the antibodies directed against the globoside antigen on suppressor T cells stimulate the suppressor T cells, and that anti-globoside antibodies in cancer sera may play a role in causing immunodeficiency in cancer patients.4
Cat# Size Price Qty Buy
1960 50 ul £351.56

Additional Information

Property Value or Rating
Product Size 50 ul
Manufacturer Matreya, LLC
Formula Weight 0
Solvent none
Source rabbit
Purity serum, not purified
Analytical Methods ELISA, TLC immunoblotting
Solubility water
Physical Appearance Purified globoside
Storage -20°C
References

1. H. Yoshino, et al.,Journal of Neurochem., Vol 61, pp. 658, 1993 
2. S. Kusunoki, et al., Neurology, Vol. 37, pp.1795, 1987 
3. A. Hellberg, J. Poole, and M. Olsson, The Journal of Biological Chemistry, Vol. 277, pp. 29455, 2002 
4. R. Noguchi, M.D., N. Shinomiya, M.D., K. Nagai, Ph.D. and J. Yata, M.D., Japanese Journal of Clinical Oncology, Vol. 13, pp.335-342, 1983

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