3-Hydroxytetradecanoic acid3-Hydroxytetradecanoic acid
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3-Hydroxytetradecanoic acid

3-Hydroxy C14:0 fatty acid

This 3-hydroxytetradecanoic acid is a high purity standard that is useful for the investigation of disorders and diseases. 3- Hydroxytetradecanoic acid is used as a biomarker for the molecular subunit endotoxin Lipid-A (where it is the most abundant saturated fatty acid) which is responsible for toxicity.1 Polyhydroxyalkenoates, polyesters produced by bacteria fermentation, are used for carbon and energy storage and are of interest in studies regarding their synthesis, properties and mechanisms. Medium chain-length polyhydroxyalkenoate monomers such as 3-hydroxytetradecanoic acid may have some pharmaceutical properties. 3-hydroxy fatty acids are used as biomarkers for fatty acid oxidative disorders of both the long- and short-chain 3- hydroxy-acyl-CoA dehydrogenases.2,3
Cat# Size Price Qty Buy
1735 25 mg £178.13

Additional Information

Property Value or Rating
Product Size 25 mg
Manufacturer Matreya, LLC
Empirical Formula C14H28O3
CAS# 3422-31-9
Formula Weight 244.4
Solvent none
Source synthetic
Purity 98+%
Analytical Methods TLC, GC, identity confirmed by MS
Natural Source Synthetic
Melting Point 80-81°C
Solubility chloroform, methanol, ethanol
Physical Appearance A neat solid
Storage -20°C
References

1. D. Kirschner, S. Que Hee, and C. Clark “Method for detecting the 3-hydroxymyristic acid component of the endotoxins of gram-negative bacteria in compost samples” Am Ind Hyg Assoc J, vol. 46(12) pp. 741-746, 1985 
2. P. Jones et al. “Improved Stable Isotope Dilution-Gas Chromatography-Mass Spectrometry Method for Serum or Plasma Free 3-Hydroxy-Fatty Acids and Its Utility for the Study of Disorders of Mitochondrial Fatty Acid beta-Oxidation” Clinical Chemistry, vol. 46, pp. 149-155, 2000 
3. P. Jones et al. “Accumulation of free 3-hydroxy fatty acids in the culture media of fibroblasts from patients deficient in long-chain l-3- hydroxyacyl-CoA dehydrogenase: a useful diagnostic aid” Clinical Chemistry, vol. 47(7) pp. 1190-1194, 2001

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