3-Hydroxyhexanoic acid3-Hydroxyhexanoic acid
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3-Hydroxyhexanoic acid

3-Hydroxy C6:0 fatty acid

This 3-hydroxyhexanoic acid is a high purity standard that is useful for the investigation of disorders and diseases. Polyhydroxyalkenoates, polyesters produced by bacteria fermentation, are used for carbon and energy storage and are of interest in studies regarding their synthesis, properties and mechanisms. Short chain-length polyhydroxyalkenoate monomers such as 3-hydroxyhexanoic acid may have pharmaceutical properties. The biologically natural chiral (R)-3-hydroxyhexcanoic acid is an intermediate in fatty acid biosynthesis. 3-hydroxyhexanoic acid has been found in patients with ketoacidosis.1 3- hydroxy fatty acids are used as biomarkers for fatty acid oxidative disorders of both the long- and short-chain 3-hydroxyacyl- CoA dehydrogenases.2,3
Cat# Size Price Qty Buy
1747 25 mg £178.13

Additional Information

Property Value or Rating
Product Size 25 mg
Manufacturer Matreya, LLC
Empirical Formula C6H12O3
CAS# 10191-24-9
Formula Weight 132.2
Solvent none
Source synthetic
Purity 98+%
Analytical Methods TLC, GC
Natural Source Synthetic
Solubility chloroform, ethanol, methanol
Physical Appearance A neat liquid
Storage -20°C
References

1. T. Niwa, K. Yamada, T. Ohki, H. Furukawa “3-Hydroxyhexanoic acid: an abnormal metabolite in urine and serum of diabetic ketoacidotic patients” Journal of Chromatography, vol. 337 pp. 1-7, 1985 
2. P. Jones et al. “Improved Stable Isotope Dilution-Gas Chromatography-Mass Spectrometry Method for Serum or Plasma Free 3-Hydroxy-Fatty Acids and Its Utility for the Study of Disorders of Mitochondrial Fatty Acid beta-Oxidation” Clinical Chemistry, vol. 46, pp. 149-155, 2000 
3. P. Jones et al. “Accumulation of free 3-hydroxy fatty acids in the culture media of fibroblasts from patients deficient in long-chain l-3-hydroxyacyl-CoA dehydrogenase: a useful diagnostic aid” Clinical Chemistry, vol. 47(7) pp. 1190-1194, 2001

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