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XAV-939

Selleck

XAV-939 (S1180-GRP)

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Description

XAV-939 (NVP-XAV939) selectively inhibits Wnt/β-catenin-mediated transcription through tankyrase1/2 inhibition with IC50 of 11 nM/4 nM in cell-free assays, regulates axin levels and does not affect CRE, NF-κB or TGF-β.

Specifications

Manufacturer Cat# S1180
Target Wnt/beta-catenin