TRAIL R4 (Intracellular Domain) Blocking Peptide
£103.13
TRAIL R4 (Intracellular Domain) Blocking Peptide (D266-50ug)
Product
| Cat # D266-50ug | Size 50 µg |
Price
£103.13
|
Qty
|
Description
TNF-related apoptosis-inducing ligand receptor 4 (TRAIL R4) is a decoy receptor that negatively regulate TRAIL-induced cytotoxicity by competing for ligand binding with TRAIL-R1 and TRAIL-R2.1 TRAIL R4 is expressed mainly on CD8+ and NK cells and induces apoptosis in many tumour cells, but not in normal cells. TRAIL-R4 contains partially truncated death domain and therefore is unable to induce apoptosis and serves as a negative regulator of apoptotic signaling by impairment death-inducing signaling complex (DISC) processing.1,2
Specifications
| Manufacturer Cat# | D266 |
|---|---|
| Product Size | 50 µg |
| Formulation | This peptide is formulated in PBS pH 7.2 (0.01 M Sodium Phosphate, 0.13 M NaCl) containing 0.1% bovine serum albumin and 0.02% sodium azide. |
| Alternate Names | TNF-Related Apoptosis-Inducing Ligand Receptor 4 TNFRelated ApoptosisInducing Ligand Receptor 4 TNF Related Apoptosis Inducing Ligand Receptor 4 TRAIL R4 Intracellular Domain Blocking Peptide Blocking Peptide TNF-Related Apoptosis-Inducing Ligand Receptor 4 TNFRSF10D Decoy Receptor 2 DCR2 CD264 TRUNDD TR4 TRAIL R4 Human TRAIL R4 Intracellular Domain Blocking Peptide Blocking Peptide TNFRelated ApoptosisInducing Ligand Receptor 4 TNFRSF10D Decoy Receptor 2 DCR2 CD264 TRUNDD TR4 TRAIL R4 Human TRAIL R4 Intracellular Domain Blocking Peptide Blocking Peptide TNF Related Apoptosis Inducing Ligand Receptor 4 TNFRSF10D Decoy Receptor 2 DCR2 CD264 TRUNDD TR4 TRAIL R4 Human TRAIL R4 Intracellular Domain Blocking Peptide TRAIL R4 Intracellular Domain Blocking Peptide TRAIL R4 TRAIL R4 Intracellular Domain Blocking Peptide TNFRSF10D Decoy Receptor 2 DCR2 CD264 TRUNDD TR4 TRAIL R4 Intracellular Domain Blocking Peptide |
| Target | TNF-Related Apoptosis-Inducing Ligand Receptor 4 |
| Storage | Store this peptide in working aliquots at -20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. |
| Protein | TNF-Related Apoptosis-Inducing Ligand Receptor 4 |