SiR-NHS ester (CY-SC003)

SiR-NHS is the N-hydroxysuccinimidyl ester (NHS) form of the fluorophore silicon rhodamine (SiR)1) . Sir-NHS reacts readily with primary and secondary amines allowing preparing custom SiR conjugates via amide bond formation. Small molecules, peptides and oligonucleotides bearing an amino group or proteins can be conjugated to SiR-NHS. The key features of SiR-NHS are i) far-red absorption and emission wavelengths, ii) high extinction coefficient, iii) high photostability and iv) compatibility with superresolution microscopy (STED & SIM)2). The combination of those properties put SiR-NHS at the leading edge of excellence.