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SiR-Maleimide

Spirochrome

SiR-Maleimide (SC011-GRP)

View Data Sheet
SiR-maleimide is the 2-maleimidoethyl derivative of SiR. It reacts with thiols and allows the preparation of custom SiR-conjugates.

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Description

SiR-maleimide is the 2-maleimidoethyl derivative of the fluorophore silicon rhodamine (SiR). Sir-maleimide reacts with thiols to form covalent conjugates. Small molecules, peptides, oligonucleotides or proteins bearing a free thiol can be conjugated to SiR-maleimide. SiR excitation and emission are compatible with GFP and/or m-cherry fluorescent proteins. It can be imaged with a standard Cy5 filterset.

Properties

λabs 652 nm
εmax 1.0·105 mol-1·cm-1
λfl 674 nm
MW =594.2 g/mol
CF260 = 0.116
CF280 = 0.147

Specifications

Manufacturer Cat# SC011