SiR-Alkyne

SiR-Alkyne

SiR-alkyne is a clickable derivative of SiR. It reacts with azides and allows the preparation of custom SiR-conjugates.

SiR-alkyne is the N-propargylcarboxamide derivative of the fluorophore silicon rhodamine (SiR). Sir-alkyne reacts with azide derivatives in the presence of copper (I) to form 1,2,3-triazoles linkage. Small molecules, peptides, oligonucleotides or proteins bearing the appropriate azide can be conjugated to SiR-alkyne. SiR excitation and emission are compatible with GFP and/or m-cherry fluorescent proteins. It can be imaged with a standard Cy5 filterset.

Properties

λabs 652 nm
εmax 1.0·105 mol-1·cm-1
λfl 674 nm
MW =509.7 g/mol
CF260 = 0.116
CF280 = 0.147

Cat# Size Price Qty Buy
SC010-1 1 mg
£278.80
SC010-5 5 mg
£632.40

Additional Information

Property Value or Rating
Manufacturer Cat# SC010
Manufacturer Spirochrome AG

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