Active Recombinant Human Latent TGF-beta 1(C33S) Protein
Active Recombinant Human Latent TGF-beta 1(C33S) Protein (RP00161-GRP)
Active Recombinant Human Latent TGF-beta 1(C33S) Protein is produced by HEK293 expression system. The target protein is expressed with sequence (Leu30-Ser390(C33S)) of human TGF-beta 1 (Accession #NP_000651.3) fused with an 8×His tag at the N-terminus.
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Description
Active Recombinant Human Latent TGF-beta 1(C33S) Protein is produced by HEK293 expression system. The target protein is expressed with sequence (Leu30-Ser390(C33S)) of human TGF-beta 1 (Accession #NP_000651.3) fused with an 8×His tag at the N-terminus.
Specifications
| Manufacturer Cat# | RP00161 |
|---|---|
| Bio-Activity | 1.Measured by its ability to inhibit cell proliferation of TF-1 human erythroleukemic cells. The ED50 for this effect is typically 0.5-2 ng/mL, corresponding to a specific activity of 5.0×105~2.0×106 units/mg.|2.Measured by its binding ability in a functional ELISA. Immobilized recombinant human TGFB1 at 2 μg/mL (100 μL/well) can bind recombinant human TGFBR2 with a linear range of 1-5 ng/mL.|3.Measured by its ability to inhibit the IL-4(Catalog: RP01161)-dependent proliferation of HT-2 mouse T cells. The ED50 for this effect is 9.75-39 ng/mL, corresponding to a specific activity of 2.6×104~1.0×105 units/mg. |
| Alternate Names | TGFB1, CED, DPD1, LAP, TGFB, TGFbeta, transforming growth factor beta-1,TGF-beta 1,CED,DPD1,LAP,TGFB,TGFbeta,TGF-β |
| Reactivity | Human |
| Gene ID | 7040 |
| Swiss Prot | P01137 |
