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Recombinant Human NRG1-β1

£417.19

Recombinant Human NRG1-β1 (N188-50ug)

Leinco Technologies Inc
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Product
Cat #  N188-50ug Size  50 µg Price 
£417.19
Qty 

Description

Neuregulin/Heregulin is a family of related growth factors that are differentially spliced variants of four genes: NRG1, NRG2, NRG3 and NRG4. The longest forms of NRG contains several different modular domains and tissue-specific splicing results in many NRG isoforms containing different sets of these domains. Alternative splicing produces two types of EGF domain, designated a and b. HRG-Beta1 contains an Ig domain and an EGF domain necessary for direct binding to receptor tyrosine kinases erbB-3 and erbB-4. HRG-Beta1 binding causes erbB-3 and erbB-4 to dimerize with erbB-2 (Her2/neu) and thereby regulates the phosphorylation of erbB-2 tyrosines. HRG-Beta1 stimulates proliferation and motility of breast cancer cells and plays a role in wound healing by stimulating epidermal migration and differentiation of epidermal cells and by stimulating the expression of integrins in the epidermis.

Specifications

Manufacturer Leinco Technologies Inc
Manufacturer Cat# N188
Product Size 50 µg
Formulation This recombinant protein was lyophilized from a 0.2 μm filtered solution in 35% acetonitrile (CH3CN) and 0.1% trifluoroacetic acid (TFA).
Alternate Names Neuregulin 1-b b beta1 Neuregulin 1b b beta1 Neuregulin 1 b b beta1 Recombinant Human NRG1-b b beta1 NRG1-b b beta1 NRG1b b beta1 NRG1 b b beta1 Recombinant Human NRG1-b b beta1 HRG1-b b beta1 Heregulin 1-b b beta1 Extracellular Domain HRG Breast Cancer Cell Differentiation Factor p45 Acetylcholine Receptor Inducing Activity ARIA Glial Factor Neu Differentiation Factor HRG1b b beta1 Heregulin 1b b beta1 Extracellular Domain HRG Breast Cancer Cell Differentiation Factor p45 Acetylcholine Receptor Inducing Activity ARIA Glial Factor Neu Differentiation Factor HRG1 b b beta1 Heregulin 1 b b beta1 Extracellular Domain HRG Breast Cancer Cell Differentiation Factor p45 Acetylcholine Receptor Inducing Activity ARIA Glial Factor Neu Differentiation Factor Recombinant Human NRG1-b b beta1 Recombinant Protein Neuregulin 1-b b beta1 HRG1-b b beta1 Heregulin 1-b b beta1 Extracellular Domain HRG Breast Cancer Cell Differentiation Factor p45 Acetylcholine Receptor Inducing Activity ARIA Glial Factor Neu Differentiation Factor NRG1-b b beta1 Human NRG1-b b beta1 Recombinant Human NRG1-b b beta1 Recombinant Protein Neuregulin 1b b beta1 HRG1b b beta1 Heregulin 1b b beta1 Extracellular Domain HRG Breast Cancer Cell Differentiation Factor p45 Acetylcholine Receptor Inducing Activity ARIA Glial Factor Neu Differentiation Factor NRG1b b beta1 Human NRG1b b beta1 Recombinant Human NRG1b b beta1 Recombinant Protein Neuregulin 1 b b beta1 HRG1 b b beta1 Heregulin 1 b b beta1 Extracellular Domain HRG Breast Cancer Cell Differentiation Factor p45 Acetylcholine Receptor Inducing Activity ARIA Glial Factor Neu Differentiation Factor NRG1 b b beta1 Human NRG1 b b beta1 Recombinant Human NRG1 b b beta1 Recombinant Human NRG1-b b beta1
Target NRG1-beta 1
Storage -20°C to -70°C
Protein NRG1-beta 1