Recombinant Human Noggin/NOG Protein
Recombinant Human Noggin/NOG Protein (RP01237-GRP)
Products
Description
Recombinant Human Noggin/NOG Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Gln28-Cys232) of human Noggin (Accession #NP_005441.1) fused with a 6×His tag at the C-terminus.
Specifications
| Manufacturer | Abclonal Biotechnology |
|---|---|
| Manufacturer Cat# | RP01237 |
| Bio-Activity | 1.Measured by its binding ability in a functional ELISA. Immobilized Human BMP2 at 1 μg/mL (100 μL/well) can bind Noggin with a linear range of 2-57 ng/mL.|2. Measured by its binding ability in a functional ELISA.Immobilized Human BMP4 at 0.5 μg/mL (100 μL/well) can bind Noggin with a linear range of 4-47 ng/mL.|3.Measured by its binding ability in a functional ELISA. Immobilized Human Noggin at 1 μg/mL (100 μL/well) can bind Noggin Rabbit pAb with a linear range of 1-3.5 ng/mL.|4. Measured by its ability to inhibit BMP-4-induced alkaline phosphatase production by ATDC5 mouse chondrogenic cells. The ED50 for this effect is 13.28-53.12 ng/mL in the presence of 50 ng/mL of recombinant human BMP-4, corresponding to a specific activity of 1.88×104-7.53×104 units/mg. |
| Alternate Names | NOG,SYM1,SYNS1,SYNS1A,noggin |
| Reactivity | Human |
| Gene ID | 9241 |
| Swiss Prot | Q13253 |