Recombinant Human MIP-1α
Recombinant Human MIP-1α (M161-GRP)
Products
Description
Macrophage inflammatory protein 1 alpha (MIP-1α), also known as CCL3, is a member of the chemokine family (1). Its primary function is as a monocyte chemoattractant, but reports have also demonstrated chemoattractant and adhesive effects by MIP-1α on CD8 T cells, B cells and eosinophils. MIP-1α has been identified as a stem cell inhibitory factor that can block the proliferation of hematopoietic stem cells (2). The functional receptor for MIP-1α is CCR1 and CCR5 and it is has been shown to interact with CCL4 (3). Following acute lung injury in rats, MIP-1α stimulates production of TNF-alpha, which in turn up-regulates vascular adhesion molecules required for neutrophil influx (4). MIP-1α may have a potential role in host defense as a direct antiviral agent. It has been reported to show a significant direct antiviral activity against HSV-1(5).
Specifications
| Manufacturer | Leinco Technologies Inc |
|---|---|
| Manufacturer Cat# | M161 |
| Formulation | This recombinant protein solutiion is supplied as a 0.2 μm filtered solution in 30% acetonitrile (CH3CN) and 0.1% trifluoroacetic acid (TFA). |
| Alternate Names | G0S19-1 LD78Alpha MIP1A SCYA3 CCL3 G0S191 LD78Alpha MIP1A SCYA3 CCL3 G0S19 1 LD78Alpha MIP1A SCYA3 CCL3 Recombinant Human MIP-1a a alpha MIP-1a a alpha MIP1a a alpha MIP 1a a alpha Recombinant Human MIP-1a a alpha Macrophage Inflammatory Protein 1 Alpha Recombinant Human MIP-1a a alpha Recombinant Protein Macrophage Inflammatory Protein 1 Alpha G0S19-1 LD78Alpha MIP1A SCYA3 CCL3 MIP-1a a alpha Human MIP-1a a alpha Recombinant Human MIP-1a a alpha Recombinant Protein Macrophage Inflammatory Protein 1 Alpha G0S191 LD78Alpha MIP1A SCYA3 CCL3 MIP1a a alpha Human MIP1a a alpha Recombinant Human MIP1a a alpha Recombinant Protein Macrophage Inflammatory Protein 1 Alpha G0S19 1 LD78Alpha MIP1A SCYA3 CCL3 MIP 1a a alpha Human MIP 1a a alpha Recombinant Human MIP 1a a alpha Recombinant Human MIP-1a a alpha |
| Target | MIP-1 alpha |
| Storage | -20°C to -70°C |
| Protein | MIP-1 alpha |