Recombinant Human IL-5
Recombinant Human IL-5 (I-187-GRP)
Products
Description
IL-5 is a 26 kD TH2 cytokine and a homodimeric glycoprotein that is part of the hematopoietic family. IL-5 stimulates B cell growth as well as increases Ig secretion. It is the main factor that promotes the terminal differentiation of eosinophil progenitors and enhances the effector capacity of mature eosinophils. IL-5 is a major regulator of eosinophil accumulation in tissues. In fact, in Hodgkin lymphoma, the characteristically observed eosinophilia is suspected to result from an increased production of IL-5. IL-5 may also be the cause of several allergic diseases including asthma, where it is thought that eosinophils have a significant role in the disease pathology. There are several mAbs currently in use that target IL-5 for the treatment of severe eosinophilic asthma.
Specifications
| Manufacturer | Leinco Technologies Inc |
|---|---|
| Manufacturer Cat# | I-187 |
| Formulation | This recombinant protein solution was 0.2 µm filtered and formulated in modified Dulbecco’s phosphate buffered saline (1X PBS) pH 7.2 – 7.3 with no calcium, magnesium, or preservatives present. |
| Alternate Names | Interleukin-5 Interleukin5 Interleukin 5 Recombinant Human IL-5 IL-5 IL5 IL 5 Recombinant Human IL-5 EDF BCDFII TRF Recombinant Human IL-5 Recombinant Protein Interleukin-5 EDF BCDFII TRF IL-5 Human IL-5 Recombinant Human IL-5 Recombinant Protein Interleukin5 EDF BCDFII TRF IL5 Human IL5 Recombinant Human IL5 Recombinant Protein Interleukin 5 EDF BCDFII TRF IL 5 Human IL 5 Recombinant Human IL 5 Recombinant Human IL-5 |
| Storage | -20°C to -70°C |
| Protein | IL-5 |