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Recombinant Human IL-23/IL-12B&IL-23A Protein

Recombinant Human IL-23/IL-12B&IL-23A Protein (RP01160-GRP)

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Description

Active Recombinant Human IL-12B&IL-23A Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Ile23-Ser328&Arg20-Pro189) of human IL-23 (Accession #NP_002178.2/NP_057668.1) fused with a 6×His tag at the N-terminus(IL23A).

Specifications

Manufacturer Abclonal Biotechnology
Manufacturer Cat# RP01160
Bio-Activity 1.Measured by its binding ability in a functional ELISA.Immobilized Human IL-12B&IL-23A at 5μg/mL (100 μL/well) can bind Human IL23R with a linear range of 4-135 ng/ml.|2.Measured by its ability to induce IL-17 secretion by mouse splenocytes. The ED50 for this effect is 21.23-84.94 ng/mL, corresponding to a specific activity of 1.17×104~4.71×104 units/mg.
Alternate Names IL-23 p19/IL-12 p40,IL23,SGRF ,IL-23 alpha & IL-12 beta
Reactivity Human
Gene ID 3593&51561
Swiss Prot P29460&Q9NPF7