Recombinant Human IL-2 Rβ
Recombinant Human IL-2 Rβ (I-553-GRP)
Products
Description
CD122 is a 70-75 kD IL-2 receptor β chain that is a type I membrane protein. CD122 is involved in T cell-mediated immune responses and its activation increases proliferation of CD8+ effector T cells. It exists in three forms with varying degrees of binding affinity with IL-2. The low affinity form is a monomer of the α subunit and has no involvement in signal transduction. The intermediate affinity form is a γ/β heterodimer and the high affinity form is an α/β/γ heterotrimer. The intermediate and high affinity forms of the receptor are involved in receptor-mediated endocytosis and transduction of mitogenic signals from interleukin 2. This protein also interacts with the IL-15 receptor.
Specifications
| Manufacturer | Leinco Technologies Inc |
|---|---|
| Manufacturer Cat# | I-553 |
| Formulation | This recombinant protein was 0.2 µm filtered and lyophilized from modified Dulbecco’s phosphate buffered saline (1X PBS) pH 7.2 – 7.3 with no calcium, magnesium, or preservatives. |
| Alternate Names | Interleukin-2 Receptor Beta Interleukin2 Receptor Beta Interleukin 2 Receptor Beta Recombinant Human IL-2 Rb b beta IL-2 Rb b beta IL2 Rb b beta IL 2 Rb b beta Recombinant Human IL-2 Rb b beta IL2RB CD122 P70-75 IL2RB CD122 P7075 IL2RB CD122 P70 75 Recombinant Human IL-2 Rb b beta Recombinant Protein Interleukin-2 Receptor Beta IL2RB CD122 P70-75 IL-2 Rb b beta Human IL-2 Rb b beta Recombinant Human IL-2 Rb b beta Recombinant Protein Interleukin2 Receptor Beta IL2RB CD122 P7075 IL2 Rb b beta Human IL2 Rb b beta Recombinant Human IL2 Rb b beta Recombinant Protein Interleukin 2 Receptor Beta IL2RB CD122 P70 75 IL 2 Rb b beta Human IL 2 Rb b beta Recombinant Human IL 2 Rb b beta Recombinant Human IL-2 Rb b beta |
| Antigen | CD122 is expressed on NK cells and at lower levels by T lymphocytes, B lymphocytes, monocytes, and macrophages. |
| Storage | -20°C to -70°C |
| Protein | IL-2 R beta |