Recombinant Human IL-12 Rβ1
£445.31
Recombinant Human IL-12 Rβ1 (I-592-100ug)
Product
| Cat # I-592-100ug | Size 100 µg |
Price
£445.31
|
Qty
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Description
Interleukin 12 receptor, beta 1 (IL12RB1), also known as CD212, is a type I transmembrane protein that belongs to the gp130/G-CSF receptor family. It is a common subunit of both the IL-12 and IL-23 receptor complexes which play roles in T cell mediated inflammatory reactions (1). IL12RB1 binds IL-12 with low affinity and is involved in IL-12 transduction (2). In association with IL23R, it forms the IL-23 receptor complex which functions in IL-23 signal transduction probably through activation of the Jak-STAT signaling cascade (3). IL12RB1 is expressed on activated T cells, B cells, NK cells, macrophages, and microglia. Defects in IL12RB1 are generally associated with selective susceptibility to weakly pathogenic mycobacteria and Salmonella species (4). Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
Specifications
| Manufacturer | Leinco Technologies Inc |
|---|---|
| Manufacturer Cat# | I-592 |
| Product Size | 100 µg |
| Formulation | This recombinant protein was 0.2 µm filtered and lyophilized from modified Dulbecco’s phosphate buffered saline (1X PBS) pH 7.2 – 7.3 with no calcium, magnesium, or preservatives. |
| Alternate Names | Interleukin-12 Receptor Beta 1 Interleukin12 Receptor Beta 1 Interleukin 12 Receptor Beta 1 Recombinant Human IL-12 Rb b beta1 IL-12 Rb b beta1 IL12 Rb b beta1 IL 12 Rb b beta1 Recombinant Human IL-12 Rb b beta1 IL12RB1 CD212 IL-12R-BETA1 IL12RB MGC34454 IL12RB1 CD212 IL12RBETA1 IL12RB MGC34454 IL12RB1 CD212 IL 12R BETA1 IL12RB MGC34454 Recombinant Human IL-12 Rb b beta1 Recombinant Protein Interleukin-12 Receptor Beta 1 IL12RB1 CD212 IL-12R-BETA1 IL12RB MGC34454 IL-12 Rb b beta1 Human IL-12 Rb b beta1 Recombinant Human IL-12 Rb b beta1 Recombinant Protein Interleukin12 Receptor Beta 1 IL12RB1 CD212 IL12RBETA1 IL12RB MGC34454 IL12 Rb b beta1 Human IL12 Rb b beta1 Recombinant Human IL12 Rb b beta1 Recombinant Protein Interleukin 12 Receptor Beta 1 IL12RB1 CD212 IL 12R BETA1 IL12RB MGC34454 IL 12 Rb b beta1 Human IL 12 Rb b beta1 Recombinant Human IL 12 Rb b beta1 Recombinant Human IL-12 Rb b beta1 |
| Target | IL-12 R beta |
| Applications | ELISA Cap |
| Storage | -20°C to -70°C |
| Protein | IL-12 R beta |