Recombinant Human IGF-BP7
£464.06
Recombinant Human IGF-BP7 (I-335-25ug)
Product
| Cat # I-335-25ug | Size 25 µg |
Price
£464.06
|
Qty
|
Description
Insulin-like growth factor binding protein 7 (IGFBP7), also known as Mac25 and IGFBP-rp1, is a secretory protein. IGFBP7 is expressed in a wide range of normal human tissues with very high levels in HEVs of blood vessels in the secondary lymphoid tissues. IGFBP7 suppresses growth and colony formation of prostate and breast cancer cell lines through an IGF independent mechanism, which causes a delay in the G1 phase of the cell cycle and increased apoptosis. (1-2). The expression of IGFBP7 is upregulated in senescing epithelial cells and by retinoic acid (3). It plays a role in skeletal myogenesis by binding to IGF in a manner that inhibits IGF induced differentiation of skeletal myoblasts, without affecting IGF induced proliferation. IGFBP7 also interacts with heparin sulfate proteoglycans, type IV collagen and specific chemokines. It has also been implicated in angiogenisis.
Specifications
| Manufacturer | Leinco Technologies Inc |
|---|---|
| Manufacturer Cat# | I-335 |
| Product Size | 25 µg |
| Formulation | This recombinant protein was 0.2 µm filtered and lyophilized from modified Dulbecco’s phosphate buffered saline (1X PBS) pH 7.2 – 7.3 with no calcium, magnesium, or preservatives present. |
| Alternate Names | IGF-BP7 IGFBP7 IGF BP7 Recombinant Human IGF-BP7 IBP-7 Mac25 IGF Binding Protein Related Protein-1 IGFBPrP1 FSTL2 IGFBP-7 IGFBP-7v PSF IBP7 Mac25 IGF Binding Protein Related Protein1 IGFBPrP1 FSTL2 IGFBP7 IGFBP7v PSF IBP 7 Mac25 IGF Binding Protein Related Protein 1 IGFBPrP1 FSTL2 IGFBP 7 IGFBP 7v PSF Recombinant Human IGF-BP7 Insulin-Like Growth Factor-Binding Protein 7 InsulinLike Growth FactorBinding Protein 7 Insulin Like Growth Factor Binding Protein 7 Recombinant Human IGF-BP7 Recombinant Protein Insulin-Like Growth Factor-Binding Protein 7 IBP-7 Mac25 IGF Binding Protein Related Protein-1 IGFBPrP1 FSTL2 IGFBP-7 IGFBP-7v PSF IGF-BP7 Human IGF-BP7 Recombinant Human IGF-BP7 Recombinant Protein InsulinLike Growth FactorBinding Protein 7 IBP7 Mac25 IGF Binding Protein Related Protein1 IGFBPrP1 FSTL2 IGFBP7 IGFBP7v PSF IGFBP7 Human IGFBP7 Recombinant Human IGFBP7 Recombinant Protein Insulin Like Growth Factor Binding Protein 7 IBP 7 Mac25 IGF Binding Protein Related Protein 1 IGFBPrP1 FSTL2 IGFBP 7 IGFBP 7v PSF IGF BP7 Human IGF BP7 Recombinant Human IGF BP7 Recombinant Human IGF-BP7 |
| Target | IGFBP-7 |
| Applications | ELISA Cap |
| Storage | -20°C to -70°C |
| Protein | IGFBP-7 |