Recombinant Human CX3CL1/Fractalkine (FKN)
£417.19
Recombinant Human CX3CL1/Fractalkine (FKN) (F1030-25ug)
Product
| Cat # F1030-25ug | Size 25 µg |
Price
£417.19
|
Qty
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Description
Fractalkine (FKN) is a transmembrane mucin-chemokine hybrid molecule expressed on activated endothelium1 that mediates attachment and firm adhesion of T cells, monocytes and NK cells.2 FKN plays an important proinflammatory role in rheumatoid arthritis (RA) pathogenesis as characterized by induction of synovial angiogenesis, chemotaxis, activation of monocytes and T cells as well as the stimulation of proliferation and synthesis of matrix degrading enzymes (matrix metalloproteinases, MMP) in synovial fibroblasts. Fractalkine thus may represent a novel target molecule for therapeutic intervention in RA.3 FKN is also an essential biomarker for predicting the prognosis of patients with colorectal cancer (CRC).4
Specifications
| Manufacturer | Leinco Technologies Inc |
|---|---|
| Manufacturer Cat# | F1030 |
| Product Size | 25 µg |
| Concentration | 1.0 mg/ml |
| Formulation | This purified antibody is supplied in 0.01 M phosphate buffered saline (PBS), pH 7.4, containing 0.09% sodium azide. |
| Alternate Names | Recombinant Protein Fractalkine CX3CL1 NTN ABCD-3 C3Xkine CXC3 CXC3C NTT SCYD1 Neurotactin FKN Human Fractalkine (CX3CL1) Recombinant Human Fractalkine (CX3CL1) |
| Isotype | IgG |
| Clone | 176 |
| Target | CX3CL1 |
| Storage | -20°C to -70°C |
| Protein | Follicle Stimulating Hormone Alpha |