Recombinant Human EDAR
£473.44
Recombinant Human EDAR (E191-100ug)
Product
| Cat # E191-100ug | Size 100 µg |
Price
£473.44
|
Qty
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Description
Ectodysplasin A receptor (EDAR), also known as ED1R, is a cell surface receptor of the tumor necrosis factor receptor (TNFR) family. Defects in EDAR are a cause of hypohidrotic ectodermal dysplasia (HED).1 It is characterized by abnormalities in the hair, teeth and sweat glands. EDAR is also the genetic determinant of hair fiber thickness variation among Asian populations.2 EDA has two splice variants, EDA-A1 and EDA-A2, which differ by only two amino acids. Despite this minor difference, EDAR only binds to EDA-A1, whereas EDA-A2 binds to XEDAR. It mediates the activation of NF-κB and JNK and may promote caspase independent cell death.3
Specifications
| Manufacturer | Leinco Technologies Inc |
|---|---|
| Manufacturer Cat# | E191 |
| Product Size | 100 µg |
| Formulation | This recombinant protein was 0.2 µm filtered and lyophilized from modified Dulbecco’s phosphate buffered saline (1X PBS) pH 7.2 – 7.3 with no calcium, magnesium, or preservatives. |
| Alternate Names | Ectodysplasin A Receptor Recombinant Human EDAR EDAR Recombinant Human EDAR DL ED1R ED3 ED5 EDA-A1R EDA1R EDA3 FLJ94390 DL ED1R ED3 ED5 EDAA1R EDA1R EDA3 FLJ94390 DL ED1R ED3 ED5 EDA A1R EDA1R EDA3 FLJ94390 Recombinant Human EDAR Recombinant Protein Ectodysplasin A Receptor DL ED1R ED3 ED5 EDA-A1R EDA1R EDA3 FLJ94390 EDAR Human EDAR Recombinant Human EDAR Recombinant Protein Ectodysplasin A Receptor DL ED1R ED3 ED5 EDAA1R EDA1R EDA3 FLJ94390 EDAR Human EDAR Recombinant Human EDAR Recombinant Protein Ectodysplasin A Receptor DL ED1R ED3 ED5 EDA A1R EDA1R EDA3 FLJ94390 EDAR Human EDAR Recombinant Human EDAR Recombinant Human EDAR |
| Target | EDAR |
| Applications | ELISA Cap |
| Storage | -20°C to -70°C |
| Protein | EDAR |