Recombinant Human Bim L
£475.31
Recombinant Human Bim L (B621-50ug)
Product
| Cat # B621-50ug | Size 50 µg |
Price
£475.31
|
Qty
|
Description
BimL a pro-apoptotic member of the BCL-2 protein family is also called Bod, BAM, or B2L11. This protein is one of several splice variants and interacts with other members of the BCL-2 protein family, including BCL2, BCL2L1/BCL-X(L), and MCL1, and act as an apoptotic activator. Its expression can be induced by nerve growth factor (NGF), as well as by the forkhead transcription factor FKHR-L1, which suggests a role in neuronal and lymphocyte apoptosis. Transgenic studies in the mouse suggested that this protein functions as an essential initiator of the apoptosis in thymocyte-negative selection by binding and inhibiting the activity of anti-apoptoticBcl-2 family members, thereby inducing the release of cytochrome c from mitochondria.
Specifications
| Manufacturer | Leinco Technologies Inc |
|---|---|
| Manufacturer Cat# | B621 |
| Product Size | 50 µg |
| Formulation | This recombinant protein was 0.2µm filtered and is supplied in a solution of 20mM HEPES-KOH, 1mM DTT, 100mM KCL and 2% Glycerol at a pH of 8.0. |
| Alternate Names | Recombinant Protein BimL Bcl2-L-11 BAM BimL BCL2-like 11 BOD Bim BimL Human |
| Target | BIM Long |
| Applications | ELISA Cap |
| Storage | -20 to -70ºC |
| Protein | BIM Long |