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Ralometostat (TNG908)

Selleck

Ralometostat (TNG908) (E1349-GRP)

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Description

Ralometostat (TNG908) is a potent, selective, and brain-penetrant inhibitor of PRMT5 with an IC50 of 4 μM, acting through an MTA-cooperative mechanism. It also shows antitumor activity in a xenograft model.

Specifications

Manufacturer Cat# E1349
Target PRMT