Proliferating Cell Nuclear Antigen (12502P)
£135.94
Proliferating Cell Nuclear Antigen (12502P) (12502P-5ug)
Product
| Cat # 12502P-5ug | Size 5 µg |
Price
£135.94
|
Qty
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Description
PCNA is located in the nucleus and is a cofactor of DNA polymerase delta. PCNA acts as a homotrimer and helps in processing of leading strand synthesis during DNA replication. In reaction to DNA damage, PCNA is ubiquitinated and participates in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for PCNA gene. PCNA is expressed during late G1 phase, S phase of mitosis, and persists until the end of the M phase. PCNA can be induced by UV irradiation.
Specifications
| Manufacturer Cat# | 12502P |
|---|---|
| Product Size | 5 µg |
| Concentration | Lot Specific |
| Formulation | Sterile-filtered solution in 20mM Tris, pH 7.5, 2mM EDTA, and 20% glycerol. |
| Target | Proliferating Cell Nuclear Antigen |
| Applications | WB |