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Nutlin-3a

Selleck

Nutlin-3a (S8059-GRP)

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Description

Nutlin-3a ((-)-Nutlin-3), the active enantiomer of Nutlin-3, inhibits the p53/MDM2 interaction with IC50 of 90 nM in a cell-free assay. Nutlin-3a induces autophagy and apoptosis in a p53-dependent manner.

Specifications

Manufacturer Cat# S8059
Target MDM2/MDMX