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Elezanumab (Anti-RGMA)

Elezanumab (Anti-RGMA) (A2370-GRP)

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Description

Elezanumab (Anti-RGMA) is a human monoclonal antibody that selectively targets repulsive guidance molecule A (RGMa). Elezanumab potently inhibited RGMa mediated BMP signalling via the SMAD1/5/8 pathway with IC50 of 97 pM. MW: 146.44 kD.

Specifications

Manufacturer Selleck Chemicals LLC
Manufacturer Cat# A2370
Target TGF-beta/Smad