MemGlow 560: Fluorogenic Plasma Membrane Probe (MG02)

The MemGlow™ product line consists of bright & non toxic live cell membrane probes. Originally developed as the MEMBRIGHT™ probes1-3, MemGlow™ fluorogenic probes exhibit ideal microscopy characteristics including high specificity, low background, and simple application. MemGlow™ 560 has been validated with multiple microscopy techniques including epifluorescent (widefield), confocal, 2-photon, and TIRF1. MemGlow™  has been confirmed to work in fixed cells, fixed tissue, live cells, and other phospholipid membranes such as extracellular vesicles including exosomes1-3.

Features and advantages of MemGlow™ probes:

• Bright and fluorogenic
• Simple staining protocol and low working concentration
• Compatible with live and fixed cell staining
• Compatible with ex vivo and fixed tissue staining 
• Non-toxic probes permit long-term imaging and re-imaging of live cells
• Efficient labeling of filopodia and nanotubes at nanomolar concentrations
• No dye quenching steps required
• Do not alter sample biology
• Utilize cyanine or BODIPY dyes with zwitterionic membrane anchor groups
• Superior to many existing plasma membrane dyes