Major Proglucagon Fragment (MPGF) ELISA

Major Proglucagon Fragment (MPGF) is an 86-amino acid hormone secreted from the pancreas1-3. MPGF is identified as the Carboxy terminal portion of proglucagon that contains two glucagon-related sequences. The MPGF sequence is highly conserved among mammals. Tissue specific processing of proglucagon in the pancreas releases MPGF. Intestinal processing of MPGF releases the Glucagon-Like Peptides 1 and 2 (GLP-1 and GLP-2)1-5. Measuring the circulating levels of MPGF will help in understanding the defective or abnormal metabolic pathways leading to diabetes and obesity. This kit is designed to measure MPGF.

References:
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