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M3541

Selleck

M3541 (E1512-GRP)

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Description

M3541 is a potent and selective inhibitor of ATM kinase activity with an IC50 value of 0.25 nM in cell-free assays. M3541 suppresses double-strand breaks (DSB) repair, clonogenic cancer cell growth and potentiates antitumor activity of ionizing radiation in cancer cell lines.

Specifications

Manufacturer Cat# E1512
Target ATM/ATR