LipiBright 650 SMCy5-5 - Flurogenic Lipid Droplet Probe (MG12)

Intracellular lipid-rich organelles known as lipid droplets have been shown to be important both physiologically and pathologically. The LipiBright™ probes consists of bright, fluorogenic live cell dyes that stain lipid droplets. LipiBright™ probes fluoresce 300 to 1000 times brighter in an oily/lipid environment compared to aqueous solutions1. The probes are available in three different colors; yellow: LipiBright™ 530 SMCy3.5 (Em = 570-610 nm), far red: LipiBright™ 650 SMCy5.5 (Em = 680-720 nm) and near-infrared: LipiBright™ 740 SMCy7 (Em = 770-810 nm). LipiBright probes are photostable and possess narrow absorption and emission bands, a distinct advantage over the traditional Nile Red probe; thus, multicolor imaging is possible. These probes exhibit ideal characteristics for microscopy and have been validated with multiple techniques including epifluorescent (widefield), confocal, and two photon1. With high GM values (2400 to 13300), the LipiBright SMCy3.5 and SMCy5.5 probes have been confirmed to work with two photon microscopy to work in multiple models including cells and tissues1.