GW280264X
£120.75
Product
| Cat # E1012-1mg | Size 1mg |
Price
£120.75
|
Qty
|
Description
GW280264X is a potent hydroxamate inhibitor of mixed ADAM10/TACE (ADAM17). It potently blocks TACE (ADAM17) and ADAM10 with IC50s of 8.0 nM and 11.5 nM, respectively. It inhibits constitutive and PMA-inducible CX3CL1 shedding and increases adhesive properties in CX3CL1 transfected cells. Its treatment significantly improves functional recovery after spinal cord injury.
Specifications
| Product Size | 1mg |
|---|---|
| Manufacturer Cat# | E1012 |