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GSK923295

GSK923295 (S7090-GRP)

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Description

GSK923295 is a first-in-class, specific allosteric inhibitor of CENP-E kinesin motor ATPase with Ki of 3.2 nM, and less potent to mutant I182 and T183. GSK923295 induces post-mitotic apoptosis. Phase 1.

Specifications

Manufacturer Selleck Chemicals LLC
Manufacturer Cat# S7090
Target Kinesin