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GSK3987

GSK3987 (E0099-GRP)

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Description

GSK3987 is an agonist of pan LXRα/β with EC50s of 50 nM, 40 nM for LXRα-SRC1 and LXRβ-SRC1, respectively. GSK3987 increases the expression of ABCA1 and SREBP-1c and induces cellular cholesterol efflux and triglyceride accumulation.

Specifications

Manufacturer Selleck Chemicals LLC
Manufacturer Cat# E0099
Target Liver X Receptor