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GSK J1

GSK J1 (S7581-GRP)

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Description

GSK-J1 is a highly potent inhibitor of H3K27 histone demethylase JMJD3 (KDM6B) and UTX (KDM6A) with IC50 of 60 nM in cell-free assays for JMJD3 (KDM6B) , respectively, >10-fold selectivity over other tested demethylases, with IC50 of 0.95μM and 1.76μM towards JARID1B/C.

Specifications

Manufacturer Selleck Chemicals LLC
Manufacturer Cat# S7581
Target Histone Demethylase