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GS143

GS143 (S0996-GRP)

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Description

GS143 is a selective inhibitor of IκBα ubiquitination with IC50 of 5.2 μM for SCFβTrCP1-mediated IκBα ubiquitylation. GS143 suppresses NF-κB activation and transcription of target genes. GS143 exhibits anti-asthma effect.

Specifications

Manufacturer Selleck Chemicals LLC
Manufacturer Cat# S0996