GoldEnhance EM (2113-8ML)

This novel, high-quality autometallographic enhancement reagent may be used in the same manner as conventional silver enhancement reagents. However, instead of depositing silver, this product selectively deposits gold onto Nanogold® particles or colloidal gold particles. This has a number of advantages for electron microscopy, light microscopy and membrane blotting experiments: Why gold? Gold has several important advantages for electron microscopy:

• Higher density; better contrast than silver. • Improved backscatter detection of enlarged particles - more useful for SEM. • Lower background than silver enhancement in some cases. Autonucleation is minimal.
• Gold is not etched by osmium tetroxide: gold toning or other treatment is not necessary.
• Low viscosity for easy and accurate mixing of components.
• Milder pH conditions than silver enhancement: Goldenhance is used at near neutral pH.
• Goldenhance can be used in physiological buffers - gold is not precipitated by halides as silver is (however, rinsing with water first is still recommended).
• Use under normal room lighting.
• Excellent shelf life.