GoldEnhance Blots

This novel, high-quality gold autometallographic enhancement reagent may be used in the same manner as conventional silver enhancers. However, instead of depositing silver, this product selectively deposits gold onto Nanogold® or colloidal gold particles.1 Why gold? Gold has several important advantages for electron microscopy, light microscopy and membrane blotting:

• Very sensitive detection with low background. • Autonucleation is minimal - more convenient for multiple samples, or if sample access is restricted (e.g. automated processing).
• High resolution. • Much faster than chemiluminescence.
• Low viscosity for easy and accurate mixing of components.
• Milder pH conditions than silver enhancement: GoldEnhance™ is used at near neutral pH, and you can adjust the pH for better sample preservation.
• Can be used in physiological buffers - gold is not precipitated by halide solutions as silver is (however, rinsing with water first is still recommended).
• Permanent staining: does not fade.
• No autofluorescence or quenching.
• Observe with brightfield optics - simpler and less expensive than fluorescence.
• Excellent shelf life.