GNF362 (E5908-GRP)

GNF362 is a highly selective and potent orally available inhibitor of inositol trisphosphate 3’ kinase B (Itpkb) with an IC50 of 9 nM, it also inhibits Itpka and Itpkc with IC50 values of 20 nM and 19 nM, respectively. It can be used in research to study treatment for T cell-mediated autoimmune diseases.