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Gilteritinib (ASP2215)

Gilteritinib (ASP2215) (S7754-GRP)

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Description

Gilteritinib (ASP2215) is a small-molecule FLT3/AXL inhibitor with IC50 values of 0.29 nM and 0.73 nM for FLT3 and AXL, respectively. It inhibits FLT3 at an IC50 value that was approximately 800-fold more potent than the concentration required to inhibit c-KIT (230 nM).

Specifications

Manufacturer Selleck Chemicals LLC
Manufacturer Cat# S7754
Target FLT3