GelRed, Nucleic Acid Gel Staining Solution, 10,000x (1R010)

GelRed is a fluorescent nucleic acid dye that could be used instead of ethidium bromide (EtBr), dsSafe®, and others for staining dsDNA, ssDNA, or RNA in agarose gels or polyacrylamide gels. GelRed is more stable, more sensitive, and less toxic than EtBr (because of being cell membrane-impermeant) and doesn`t require a destaining step. GelRed has been validated for Southern blotting. GelRed and EtBr have virtually the same spectra (absorbance 300 nm, emission 605 nm), so one can directly replace EtBr with GelRed without changing the existing imaging system. GelRed is also compatible with downstream DNA manipulations such as restriction digest, sequencing, and cloning.