GDC-2992
£243.75
GDC-2992 (E8277-1mg)
Product
| Cat # E8277-1mg | Size 1mg |
Price
£243.75
|
Qty
|
Description
GDC-2992 (RO7656594, Compound 28A) is an orally active degrader of androgen receptor (AR) with a DC50 of 2.7 nM. It binds to AR and cereblon (CRBN), inducing AR ubiquitination and degradation. GDC-2992 also inhibits cell proliferation in VCaP cells and exhibits potential to reduce treatment resistance and disease relapse in prostate cancer.
Specifications
| Manufacturer | Selleck Chemicals LLC |
|---|---|
| Product Size | 1mg |
| Manufacturer Cat# | E8277 |
| Target | Androgen Receptor |