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GBD-9

GBD-9 (E1847-GRP)

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Description

GBD-9 is a double-mechanism efficient degrader of BTK and GSPT1 by recruiting the E3 ligase cereblon (CRBN). GBD-9 acts both as a PROTAC molecule to induce the degradation of BTK and as a molecular glue to degrade GSPT1.It exhibits anti-proliferative effects, inhibiting cancer cell survival.

Specifications

Manufacturer Selleck Chemicals LLC
Manufacturer Cat# E1847
Target E3 Ligase